Development of Poly(3,4-Ethylenedioxythiophene) (PEDOT) Electropolymerized Sorbent-Based Solid-Phase Microextraction (SPME) for the Determination of Parabens in Lake Waters by High-Performance Liquid Chromatography – Tandem Mass Spectrometry (HPLC-MS/MS)

Parabens are widely used as antimicrobial preservatives in cosmetic products and pharmaceuticals. Therefore, their presence the environment is considered to be serious determination important. This paper reports development validation of a new method based on solid-phase microextraction (SPME) high-performance liquid chromatography – tandem mass spectrometry (HPLC-MS/MS) for simultaneous five parabens (methylparaben (MP), ethylparaben (EP), propylparaben (PP), butylparaben (BP) benzylparaben (BzP)) surface water. The polymer sorbent was obtained by electropolymerization 3,4-ethylenedioxythiophene stainless steel spring support. parameters affecting extraction efficiency were optimized. Under optimal conditions, recoveries ranged from 88 98% except BzP (70%). Good linear responses with correlation coefficients (r2) exceeding 0.999. detection limits 0.004 0.28 µg L?1. successfully applied lake